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Motifs, modules, networks: Assembly and organization of regulatory signaling systems

July 11–14, 2023
Bolger Center, Potomac, Md.

• View the program schedule

Our understanding of how cellular signaling networks are organized has evolved substantially in recent years. Namely, the myriad components of signaling networks — receptors, signaling enzymes such as phosphatases and kinases, substrates and scaffolding proteins — often assemble through highly dynamic interactions involving intrinsically disordered regions and short linear sequence motifs (SLiMs). These dynamic interactions allow for rapid responses to signaling inputs and dictate systems-level properties of signaling networks. Understanding SLiM-mediated interactions has made it possible to define “substratomes” of signaling enzymes as well as interaction networks that provide novel insights into signaling platforms and cellular networking mechanisms.

This interdisciplinary conference will bring together researchers in structural biology, biochemistry, computational biology and proteomics who investigate cellular signaling networks and leverage these insights into the development of new therapeutic strategies.

Learn more

Cellular signaling networks in JBC

A specially curated collection of articles published in the Journal of Biological Chemistry in recent years showcasing the latest breakthroughs in cellular signaling networks.

Organizers

UConn Health

Dartmouth Geisel School of Medicine

Yale School of Medicine

Important dates

*Registration and housing are on a first-come, first-served basis and will remain open until capacity is reached. This may mean that the conference registration closes before the officially posted registration deadline. To secure your spot at the conference we encourage you to register early.

Conference information

• Conference will begin around 4 p.m. on July 11.
• Conference will conclude around 2 p.m. on July 14.

Registration and abstracts

• There is no onsite registration, all attendees must be registered prior to arriving at the conference.
• Registration for the conference is required at the time of abstract submission.
• Please reach out to meetings@asbmb.org if you have questions.

Health and safety

• Mask-wearing and other health and safety measures will be determined based on local, state and venue guidelines and will be communicated to attendees prior to the conference.

Getting to the Bolger Center

Airports

• (DCA) — 19.6 miles
• (IAD) — 24.5 miles
• (BWI) — 39.8 miles

Getting from the airports to the Bolger Center

All attendees are responsible for their own transportation. There will not be a shuttle provided to/from the airports/.

• Uber/Lyft/Rideshare
• Closest metro station is — 5.5 miles away from Bolger Center.

Visas

All individuals traveling from outside of the United States should apply for a visa as soon as possible and at least four to five months prior to their date of travel.

• The most up-to-date information about traveling to the U.S. can be found at the .
• Scientists visiting the U.S. may find helpful information at the .
• .

Please do not wait until you receive your registration confirmation before applying for a visa. We encourage you to apply for your visa right away if you are considering attending to avoid delays and longer than anticipated wait times.

All visitors traveling to the U.S. from  must meet all requirements of the program. .