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The Journal of Biological Chemistry’s Methods Madness tournament started off with a bang as last year’s finalist, , faced off against the tournament newcomer . fought valiantly, but their supporters’ energy just didn’t transfer into votes. Meanwhile, supporters turned up in SPECTRAcular numbers, pushing their team to the next round.

X-ray crystallographers around the world are rejoicing after ’s victory over . Votes proved to be too nonspecific for , whose supporters were unable to band together to provide support for their team. advances to the next round while fades into the background.

iced their competition, leaving #TeamMachine frozen in their tracks. Despite strategic support from , it seems too many #TeamMachine supporters had their heads in the cloud, because they couldn’t find the algorithm needed to execute a win against the defending champion. will move on to the Energetic Eight, where they will have a tough matchup against .

In this cellular showdown, lacked the factors necessary to differentiate from the other losers of the week. In contrast, was unphased by the pressure, shining bright in the win they captured. has in their frame as they focus on the next round.

copied last year’s success to defeat and advance to the next round. Supporters of #TeamChroma couldn’t match the flow rate of voters, leaving stuck in a stationary phase while their opponent mobilized. will look to amplify their success with a win over in the next round.

Resonating with their supporters, put forth a dynamic performance to secure their second win in as many years. Living up to their name, replicated last year’s performance where they also lost against in the first round. Perhaps they’ll find the winning recombination next year!

excised in the first round of the tournament and will move on to the next round. Despite their resolution to make it further this year, the win that pictured was never fully deconvolved. has their work cut out for them, facing off against the defending champion #TeamCryo.

Seq-ing a win in their tournament debut, analyzed their competition and came out victorious. Seemingly unable to shed light on a winning formula, failed to excite their supporters, resulting in their second tournament loss in as many years. Next, will match up against in the Energetic Eight round.

Round 2: The Energetic Eight

Monday, March 22

12 p.m. Eastern – #TeamNMR vs. #TeamXRC

Tuesday, March 23

12 p.m. Eastern – #TeamPCR vs. #TeamMassSpec

Wednesday, March 24

12 p.m. – #TeamLiveCell vs. #TeamOmics

Thursday, March 25

12 p.m. – #TeamCryo vs. #TeamCRISPR