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Computational and structural biology

Computational and biophysical approaches to disordered proteins
Award

Computational and biophysical approaches to disordered proteins

Nov. 14, 2024

Rohit Pappu will receive the 2025 DeLano Award for Computational Biosciences at the ASBMB Annual Meeting, April 12-15 in Chicago.

3D shapes of viral proteins point to previously unknown roles
News

3D shapes of viral proteins point to previously unknown roles

Oct. 19, 2024

A research team led by Jennifer Doudna has harnessed computational and deep-learning tools to predict the shapes of nearly 4,500 species that infect animals and humans.

Nobel for ‘breakthrough in biochemistry’
News

Nobel for ‘breakthrough in biochemistry’

Oct. 9, 2024

David Baker, Demis Hassabis and John M. Jumper received the chemistry prize for computational protein design and structure prediction.

Why AlphaFold 3 needs to be open source
Essay

Why AlphaFold 3 needs to be open source

July 7, 2024

The powerful AI-driven software from DeepMind was released without making its code openly available to scientists.

New class of antimicrobials discovered in soil bacteria
News

New class of antimicrobials discovered in soil bacteria

May 5, 2024

Scientists have mined Streptomyces for antibiotics for nearly a century, but the newly identified umbrella toxin escaped notice.

Hinton lab maps structure of mitochondria at different life stages
Member News

Hinton lab maps structure of mitochondria at different life stages

April 20, 2024

An international team determines the differences in the 3D morphology of mitochondria and cristae, their inner membrane folds, in brown adipose tissue.

From the journals: MCP
Journal News

From the journals: MCP

April 12, 2024

Three views of mass spec: analyzing secreted protein spectra, imaging mass spectrometry for clinical use and spectral libraries for MS data analysis. Read about these recent papers.

From the journals: MCP
Journal News

From the journals: MCP

March 29, 2024

Amino acids and sulfate signatures. Unveiling phosphatase substrates. Simplifying bacterial proteome profiling. Read about recent papers on these topics.

From the journals: JBC
Journal News

From the journals: JBC

March 15, 2024

Cap-snatching viruses. Membrane makeup facilitates fusion. A disordered region promotes scaffold activity. Read about recent papers on these topics.