JBC News
![From the JBC archives: Madness, indoles and mercury-based cathartics](/getattachment/e26ef62e-685d-450f-b5e4-113430cfb888/JBC-archives-02-11-25-480x270.jpg?lang=en-US&width=480&height=270&ext=.jpg)
From the JBC archives: Madness, indoles and mercury-based cathartics
A 1907 paper sought to resolve an ongoing question of whether indole, a bacterial molecule in the gut, could cause insanity if overproduced.
![From the journals: JBC](/getattachment/05f125e8-aa95-4a9e-bd9c-896b3f72923c/FTJ-JBC-02-07-25-480x270.jpg?lang=en-US&width=480&height=270&ext=.jpg)
From the journals: JBC
Linking modified cysteines to cell migration. Recognizing protein tags for degradation. Disrupting C. difficile toxin production. Read about recent JBC papers on these topics.
![Mutant RNA exosome protein linked to neurodevelopmental defects](/getattachment/dbfd7c8c-5104-4903-8e97-2c82f9d97262/Mutant-RNA-exosome-protein-480x270.jpg?lang=en-US&width=480&height=270&ext=.jpg)
Mutant RNA exosome protein linked to neurodevelopmental defects
Researchers at Emory University find that a missense mutation impairs RNA exosome assembly and translation and causes neurological disease.
![Breaking through limits in kinase inhibition](/getmedia/bf5312f6-88ea-4387-b0bc-0665c6995801/Shapiro-thumb.jpg?width=480&height=270&ext=.jpg)
Breaking through limits in kinase inhibition
Paul Shapiro, the first speaker on ASBMB Breakthroughs, a new webinar series highlighting research from ASBMB journals, discussed taking ideas and discoveries from basic science research toward clinical applications.
![Liver enzyme holds key to adjusting to high-protein diets](/getmedia/45bc9cd8-6f6f-4295-8e9b-21845fb2ce77/JBC-Lius-thumb.jpg?width=480&height=270&ext=.jpg)
Liver enzyme holds key to adjusting to high-protein diets
Researchers at the University of Geneva show that glutamate dehydrogenase controls blood alkalinity during fasting.
![From the journals: JBC](/getattachment/2accfb63-afb5-478a-aa8c-68dbf5b6bbd2/FTJ-JBC-01-10-25-480x270.jpg?lang=en-US&width=480&height=270&ext=.jpg)
From the journals: JBC
Histone demethylase inhibited by own sequence. MicroRNA reduces cell cycle鈥搑elated apoptosis. Multipurpose antibiotic takes on staph infections. Read about recent JBC papers on these topics.
![Toxoplasma gondii parasite uses unconventional method to make proteins for evasion of drug treatment](/getattachment/44fc02c4-4d4c-4dd6-afcd-92aedc34e597/Toxoplasma-gondii-480x270.jpg?lang=en-US&width=480&height=270&ext=.jpg)
Toxoplasma gondii parasite uses unconventional method to make proteins for evasion of drug treatment
This recent study by a team from Bill Sullivan鈥檚 lab at the Indiana University School of Medicine was named a Journal of Biological Chemistry Editor鈥檚 Pick.
![Ubiquitination by TRIM13: An ingredient contributing to diet-induced atherosclerosis](/getattachment/4862a475-32cd-43e9-8800-706fb75ff7c5/JBC-Ubiq-TRIM13-480x270.jpg?lang=en-US&width=480&height=270&ext=.jpg)
Ubiquitination by TRIM13: An ingredient contributing to diet-induced atherosclerosis
Researchers help unravel the molecular mechanism behind plaque formation in cardiovascular disease.
![From the journals: JBC](/getattachment/d71adaa5-9f76-48d0-920a-9d59afc400d3/FTJ-JBC-12-20-24-480x270.jpg?lang=en-US&width=480&height=270&ext=.jpg)
From the journals: JBC
Huntington protein interactions affect aggregation. Intrinsically disordered protein forms a scaffold. From unknown protein to curbing cancer growth. Read about recent JBC papers on these topics.