Disease mechanisms and treatments
At the Salton Sea, uncovering the culprit of lung disease
Scientists have long suspected a link between the dust and poor respiratory health. According to recent findings, the prime suspect is a naturally occurring toxin.
From the Journals: JBC
Nuclear actin affects transcription elongation. Proteostasis in Alzheimer鈥檚 disease. RNA and splicing affect cancer invasiveness. Read about recent papers on these topics.
Do ribosomal traffic jams cause Huntington鈥檚 disease?
鈥淛ust because there are a lot of cars doesn鈥檛 mean they鈥檙e all reaching their destination,鈥� a researcher points out. And so it goes with mRNA translation within mitochondria.
Finding the transcriptional basis of diet-induced obesity
A recent study shows the previously unknown role of hepatic transcription factor FOXA3 in metabolic disease.
The quest to treat and cure xerostomia
Blake Warner, chief of the Salivary Disorders Unit at the NIH talks about his lab鈥檚 efforts to develop treatments for dry mouth.
Radioactive drugs strike cancer with precision
The tumor-seeking radiopharmaceuticals are charting a new course in oncology, with promise for targeted treatments with fewer side effects.
New study discovers tiny target on RNA to short-circuit inflammation
Paper details high-throughput process for rapid screening, identification of mysterious 鈥榣ong non-coding RNA.鈥�
How to control chronic wasting disease
A prion sickness similar to mad cow is spreading rapidly through North America鈥檚 deer and elk populations. A veterinary microbiologist discusses the options for keeping it in check.
From the journals: MCP
Unlocking a metabolic disorder mystery. The many roles of lactate. Tools can unveil dementia biomarkers. Read about these recent papers.